Endocrine Abstracts

Neuroendocrine tumors (NETs) includes a broad family of tumors, the most frequent ones are in the gastrointestinal tract, lung, thymus, and pancreas. Gas-trointestinal and Pulmonary NETs may present with symptoms attributable to hormonal hypersecretion, which include intermit-tent flushing and diarrhea, or symptoms related to Cushing Syndrome. The variability of clinical manifestation may lead to late referral or misdiagnosis. In this retrospective study we analyzed 27 patient...

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder caused by germline mutations of MEN1 gene, without genotype–phenotype correlation. It is defined as the occurrence of two or more primary neuroendocrine tumors (parathyroid, enteropancreatic, pituitary), or the occurrence of one of the MEN1-associated tumors in family members of a patient with a clinical diagnosis of MEN1. Multiple parathyroid tumors with hyperparathyroidism are the most common m...

Background: Surgery is the standard treatment in patients with medullary thyroid carcinoma (MTC), 43% being biochemically cured postoperative in a large series, the most important prognostic factor being the stage of the disease.Material and methods: We present 3 cases of biochemical cured patients after surgery with different preoperative presentation. Calcitonin and carcinoembryonic antigen (CEA) were measured by chemiluminescence. Histological examina...